Publishing Media

Pronalyse is a new division of Creative Proteomics, which is an integrated CRO company with rich experience in providing drug development service for over 10 years. The company has recently announced Protein Drug Modification Analysis service to help researchers determine the modification type, modification site, and modification structure of protein drugs. Mature protein medicines have complete…

Profacgen, a state-of-the-art protein service provider that provides custom protein services in the biological sciences, recently updated its membrane protein modeling service to better assist scientists in the field of structure-based protein engineering. Membrane proteins account for one third of all genes in the human genome, and they play critical roles as receptors, enzymes, ion channels,…

In a new study, researchers from the National Institute of Dental Craniofacial Research (NIDCR) have found that blocking the function of a coagulation protein prevents bone loss caused by periodontal (gingival) disease in mice. According to animal and human data, they found that the accumulation of this clotting protein called fibrin triggers an excessive immune response…

Cellulase (β-1,4-glucan-4-glucanohydrolase) is a general term for a group of enzymes that degrade cellulose to produce glucose. Cellulase is a kind of complex enzyme, including C1 enzyme, CX enzyme and glucosidase and other components. Among them, C1 enzyme and CX enzyme can decompose cellulose into cellobiose, and glucosidase can decompose cellobiose into glucose, thereby providing…

BOC Sciences, well known as the largest supplier of pseudoUridine in the world, announces that its yearly output currently surpasses 500 kg, indicating reliable efficiency and high productivity. Along with the explosion of the COVID-19 pandemic, many vaccine companies have collaborated with BOC Sciences to obtain necessary materials such as pseudoUridine and its derivatives. PseudoUridine is universally acknowledged as the…

Australian researchers have recently solved a multi-year mystery about Parkinson’s disease. They solved the structure of a key protein that is expected to rapidly treat this incurable disease. The findings appear in Nature. For the first time, the researchers took a “live” shot of a protein called PINK1. The findings explain how this protein is…

Cornel University researchers recently made a breakthrough in the study on schizophrenia with human-derived cerebral organoids. Schizophrenia is a chronic brain disorder of hitherto unknown etiology, with typical symptoms usually appearing in early adulthood and affecting approximately 1% of the global population. Clinically, schizophrenia often presents as a syndrome with varying symptoms involving multiple impairments…

The phrase “in silico” is pseudo-Latin referring to silicon in computer chips and it has become a frequently used term describing biological or other experiments performed by computers. This is an evolution of traditional in vivo and in vitro models that were used to develop new drugs and verify pharmacological hypotheses for over a hundred years. Facing an increasing…

The most common neurodegenerative disease is Alzheimer’s disease (AD), often known as dementia. The loss of memory, learning ability, emotional regulation, and athletic ability is common in patients, all of which have a negative impact on health, families, and society. Currently, about 50 million people worldwide are suffering from AD. As the average human life…

Immunotherapy has been successfully applied clinically to treat a wide range of hematological and solid metastatic malignancies. The most widely used drugs targeting immune checkpoints, such as programmed cell death protein 1 (PD-1) and its ligand PD-L1, are effective in a subset of cancer patients. However, anti-PD-1/PD-L1 therapy has little effect on the majority of colorectal…